Day 148 of 180Week 30 of 36, WednesdayFourth quarter

Mutations and their effects

๐Ÿ”ฌ Science๐Ÿ” Practiseโฑ๏ธ about 45 minutes

Explain why some mutations change nothing and others change everything.

Reps on something already met. Short, and worth doing even on a bad evening.

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Today is rung 7 of 8 on this topic

DNA, protein synthesis and inheritance

Can do: Explains how DNA codes for proteins and predicts inheritance with a Punnett square.

Why it matters

It's the mechanism underneath everything else in biology, and the gene-to-trait chain is what most students never quite assemble.

What it looks like when it's wobbly

Knows DNA carries information but has no chain from gene to protein to trait.

โฑ๏ธ Two-minute check

"How does a change in DNA change an organism? Walk me from gene to trait."

Solid looks like: DNA โ†’ mRNA โ†’ protein โ†’ function โ†’ trait, in order.

The full activity for this topic ยท 30 minutes

Build the Chain

PaperA codon tableStrawberries and washing-up liquid for extraction, optional
  1. 1Write a short DNA sequence and transcribe it to mRNA, then translate it with a codon table.
  2. 2Change one base and translate again. Sometimes nothing changes; sometimes everything does.
  3. 3Discuss why that explains both harmless variation and genetic disease.
  4. 4Do a Punnett square for a real trait and predict ratios.
  5. 5Extract DNA from strawberries โ€” it's visible with kitchen equipment and it makes the molecule real.

If it's too hard

Punnett squares for one trait only.

If it's too easy

Dihybrid crosses, and sex-linked inheritance with a pedigree chart.

Say this

"Change one letter. Does the protein change? Sometimes it doesn't โ€” why not?"

Science practice

Week 30 at a glance

  1. Monday ยท Day 146

    ๐Ÿ”ข Math

    Model a real growth

  2. Tuesday ยท Day 147

    ๐Ÿ“– Reading

    Annotate a whole chapter

  3. Wednesday ยท Day 148

    ๐Ÿ”ฌ Science

    Mutations and their effects

  4. Thursday ยท Day 149

    โœ๏ธ Writing

    Exam paper simulation

  5. Friday ยท Day 150

    ๐Ÿงญ Study & Life Skills

    Sleep as the fixed block

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